Allergies to dust mites within specific allergens, the dog and the house, were higher in patients with low levels of vitamin D. Low levels of vitamin D also correlated with FEV 1 bass, the amount of air a person can exhale in a FEV1/FVC second, and most low, another measure of lung function. The use of inhaled steroids, oral steroids and long acting beta agonists was higher in patients with low levels of vitamin D.The researchers reviewed the electronic medical records of 100 patients with asthma in children referred to National Jewish Health. Overall, 47 per cent of them had vitamin D levels considered insufficient, to below 30 nanograms per milliliter . Seventeen % of patients had levels lower than 20 ng / mL, which is considered deficient.
Children with asthma in our study who had low levels of vitamin D were more allergic, had poorer lung function and used more drugs, said Dr. Searing. On the contrary, our results suggest that vitamin D supplementation can help reverse steroid resistance in asthmatic children and reduce the effective dose of steroids needed for our patients.
Low levels of vitamin D are associated with lower lung function and increased use of drugs in children with asthma, according to researchers at National Jewish Health. In a paper published online this week in the Journal of Allergy & Clinical Immunology, Daniel Searing, MD, and colleagues also reported that vitamin D increases the activity of corticosteroids, the drug more effective asthma control.
We raise a generation of children who may have trouble maintaining the constant attention and targeted because they are so used to being distracted, Gentile said.
Our results suggest two possible explanations, said lead author Donald Leung, MD, PhD. It could be lower levels of vitamin D contributes to increases in asthma severity, requiring more corticosteroid treatments. Or, it may be that vitamin D directly affects the activity of steroids, and that low levels of vitamin D steroids are less effective, that require more drugs in the same direction.
This study comes on the heels of another paper by professors at National Jewish Health, which has shown that low levels of vitamin D in adult patients with asthma are associated with lower lung function and reduced responsiveness to corticosteroids.